Biological v. psychosocial treatments: a myth about pharmacotherapy v. psychotherapy

Psychotherapy and pharmacotherapy in depression.

BACKGROUND Depression is a condition with various modes of treatment, including pharmacotherapy, psychotherapy, and some combination of each. The role of psychotherapy in the treatment of depression relative to the role of pharmacotherapy is not well understood, and guidelines for psychotherapy in the primary care setting differ from guidelines for specialty care. There is little evidence conce...

A Pregnant Woman with Factor V Deficiency

Sectional Anatomy Quiz - V

In this series a pictorial quiz pertaining to identification of normal anatomical structures and landmarks at a given level on the computed tomography (CT) is presented. An image depicting normal anatomy is followed by a series of images showing different pathologies. Readers are expected to identify and appreciate variation and changes in the normal anatomy in presence of a given pathology. Th...

The CC-V Flap: A Novel Technique for Augmenting a C-V Nipple Reconstruction Using a Free Dermal Graft

BACKGROUND We present a novel method for augmenting the standard C-V flap used for nipple reconstruction with a free dermal graft which aims to improve the appearance of the nipple reconstruction, decrease loss of projection and improve patient satisfaction overall. METHODS The surgical technique for performing a free dermal graft augmentation of a CV flap is described. All patients who unde...

Myosin V is a biological Brownian machine

Myosin V is a vesicle transporter that unidirectionally walks along cytoskeletal actin filaments by converting the chemical energy of ATP into mechanical work. Recently, it was found that myosin V force generation is a composition of two processes: a lever-arm swing, which involves a conformational change in the myosin molecule, and a Brownian search-and-catch, which involves a diffusive "searc...